BRIDGING SCALES THROUGH MULTISCALE MODELING: A CASE STUDY ON PROTEIN KINASE A


Phenylboronic acid conjugated multifunctional nanogels with 131I-labeling for targeted SPECT imaging and radiotherapy of breast adenocarcinoma

We report a new 131I-labeling functional platform for targeted single-photon emission computed tomography (SPECT) imaging and Audio Turntable Headshell radiotherapy of breast adenocarcinoma.In this study, polyethyleneimine (PEI) based nanogels (P.NH2 NGs) were prepared by water/oil polymerization, modified with targeted agent phenylboronic acid (PB

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Dopamine Reduces SARS-CoV-2 Replication In Vitro through Downregulation of D2 Receptors and Upregulation of Type-I Interferons

Recent evidence suggests that SARS-CoV-2 hinders immune responses via dopamine (DA)-related mechanisms.Nonetheless, studies addressing the specific role of DA in the frame of SARS-CoV-2 infection are still missing.In the present study, we investigate the role of DA in SARS-CoV-2 replication along with potential links with innate immune pathways in

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